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Bile acids / Bile salts biosynthesis & Hepatocytes
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Contents
Primary Bile Acids / Primary Bile Salts (PBAs) are synthesized in hepatocytes by two pathways: the classic pathway initiated by Cholesterol 7 alpha-hydroxylase (CYP7A1) and the alternative, neutral pathway initiated by 24-hydroxycholesterol-7 alfa hydroxylase (CYP27A1/CYP7B1)
Cholic Acid (CA) and [C…
References (Sources)
- Developmental Patterns of Fecal Bile Acids in Healthy Neonates and Children
- Environmental Chemical Contribution to the Modulation of Bile Acid Homeostasis and Farnesoid X Receptor Signaling
- Interactions between bile salts, gut microbiota, and hepatic innate immunity
- Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology
- The Liver under the Spotlight: Bile Acids and Oxysterols as Pivotal Actors Controlling MetabolismReview