meRfi®-GM
CD4+ CD25+ Treg
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Contents
Markers: CD4+, CD25+, CD62L+, CTLA-4+, FoxP3+
MHC-II-presented polysaccharide A (PSA) and possibly other T cell-dependent polysaccharides are recognized explicitly by CD4+ T cells with regulatory T cell activity
CD4+ CD25++ FOXP3 low nTreg / tTreg and CD4+ CD25+ FOXP3 high Treg (peripherally induced) both express forkhead box protein 3 (FoxP3). [Neuropilin-1](brain://PEiEogdDR0-ySo-MEKZCyA/N…
References (Sources)
- Differentiation of T Regulatory Cells by Immature Dendritic Cells
- Ex vivo isolation and characterization of Cd4+Cd25+ T cells with regulatory properties from human blood
- Expression of Helios in peripherally induced Foxp3+ regulatory T cells
- Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
- Helios expression is a marker of T cell activation and proliferation
- Naturally arising CD4+ regulatory T cells for immunologic selftolerance and negative control of immune responses
- Polysaccharide A from the Capsule of Bacteroides fragilis Induces Clonal CD4+ T Cell Expansion