meRfi®-GM
Microbial Products
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Contents
Microbial products can access immune cells locally or systemically.
The majority of genetic material produced by our commensal microbiota encodes putative proteins with currently unknown functions. These are sometimes referred to as genetic dark matter. Some microbial products with interesting and important influences on host biology have been characterized from previously undescribed genes. The high-throughput zebrafish model has proven particularly effective for mining microbial dark matter. It has uncovered the secreted bacterial proteins Amino acid importer A (AimA) a…
References (Sources)
- Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophages
- Chronic stimulation of Nod2 mediates tolerance to bacterial products
- Gene-specific control of inflammation by TLR-induced chromatin modifications
- Interactions between the microbiota and the immune system
- T Cell Responses to the Microbiota
- The scales of the zebrafish: host-microbiota interactions from proteins to populations
- Towards the Microbial Production of Plant-Derived Anticancer Drugs