Glycolysis

During glycolysis, glucose is broken down to produce energy as ATP.

Glycolytic enzymes differentially regulate the NLRP3 inflammasome
Olona et al. 2022 Trends in Immunology 43(12): 978

Productive glycolysis results in the conversion of Nicotinamide adenine dinucleotide (NAD+) to NADH, lactate secretion, and ATP production
Olona et al. 2022 Trends in Immunology 43(12): 978

Genes related to glycolysis include glut1 gene, pfkfb4 gene, and hif1A gene

Glycolysis results in the generation of pyruvate, ATP and reduced nicotinamide adenine dinucleotide (NADH) from glucose.
Tan et al. 2021b

Pyruvate can be subsequently converted into acetyl-CoA in the mitochondria to fuel the tricarboxylic acid cycle (TCA) cycle.
Tan et al. 2021b

The TCA cycle provides a source of mitochondrial NADH and flavin adenine dinucleotide (FADH 2 ) required for oxidative phosphorylation (OXPHOS), an oxygen-dependent pathway that ultimately yields 36 ATP from 1 molecule of glucose.
Tan et al. 2021b