meRfi®-GM
Inflammasomes
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Contents
Inflammasomes recognize PAMPs, DAMPs, or homeostasis-altering molecular processes (HAMPs)
Several distinct proteins (sensors) nucleate inflammasomes, including NLRP1, CARD8, NLRP3, NLRP6, NLRC4/NAIP, AIM2, [pyri…
References (Sources)
- Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome
- Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly
- Inflammasomes: mechanism of action, role in disease, and therapeutics
- Integrative inflammasome activity in the regulation of intestinal mucosal immune responsesReview
- Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developrnents
- The inflammasomes: guardians of the body
- The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation