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Metabolism was dependent on the expression of a long isoform of the bacterial enzyme cytidine deaminase (CDD L ), seen primarily in Gammaproteobacteria. Examples for bacteria with the long isoform of bacterial cytidine deaminase are Klebsiella pneumoniae, Escherichia coli K-12
Approximately 300 bacterial species express the long isoform, which is about 880 nucleotides in length, of bacterial cytidine deaminase.
see also:
Gemcitabine
Gemcitabine & Gut microbiota
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