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Deoxycholic Acid (DCA)
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Contents
Deoxycholic acid (DCA) feeding induced fibrotic changes
A set of six enzymes is necessary and sufficient for the eight-step conversion of cholic acid to Deoxycholic Acid (DCA)
Deoxycholic Acid (DCA) induces the release of 5-HT by binding to TGR5 in Enteroendocrine Cells (EEC)
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References (Sources)
- A metabolic pathway for bile acid dehydroxylation by the gut microbiome
- Bile Acids Activate NLRP3 Inflammasome, Promoting Murine Liver Inflammation or Fibrosis in a Cell Type-Specific Manner
- Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation
- Manipulation of epithelial integrity and mucosal immunity by host and microbiota-derived metabolites