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Diets that lead to obesity may send signals that cause inflammation, disrupting how immune cells and gut lining cells communicate, leading to metabolic problems. These diet-related changes can also affect gut bacteria, worsening metabolic issues. Studies show that such diets lower Interleukin-22 (IL-22), a substance that normally helps control gut bacteria by promoting the production of protective proteins and antibodies.
In experiments with mice, adding inulin to a …