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The oral microbiome ecosystem is crucial for maintaining both oral and systemic human health.
The Oral Microbiome / Mouth Microbiota may also exacerbate diseases in distal sites, such as colorectal cancer, asthma, rheumatoid arthritis, and cardiovascular disease.
It's interesting that the effects of mouth bacteria go beyond just the mouth. Many studies have shown that Periodontitis / Periodontal disease can affect the chances of getting some other health problems.
Koren and Zubeidat et al. note that the oral microbial load of newborns is higher than that of adults. Neutrophils, recruited in a Interleukin-17 Family / Interleukin-17 (IL-17)/microbiota-dependent manner, defend the permeable epithelium of the newborn. However, these neutrophils disappear during weaning, when the epithelium closes and acquires immunological characteristics of adulthood. At the same time, saliva production increases, which contributes to reducing the microbial load.
Bacteroidetes / Bacteroidota, Firmicutes (Streptococcus), Fusobacteria, and Proteobacteria predominate in the mouth
see also:
Alzheimer’s Disease (AD) & Porphyromonas gingivalis
Cancer / Tumors & Oral microbiome / Mouth microbiota
Gut microbiota & Inflammation / Inflammatory Diseases
Head & Neck squamous cell carcinoma (HNSCC)
Oral biofilms
Oral Microbiome / Mouth Microbiota & Periodontitis / Periodontal disease
Nose microbiota
Periodontitis / Periodontal disease