meRfi®-GM
Interleukin-33 (IL-33)
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Navigation
Contents
Interleukin-33 (IL-33), part of the Interleukin-1 (IL-1) / Interleukin-1 family, is crucial for driving protective CD8+ T cell responses against various RNA and DNA-Viruses. Released from fibroblastic reticular cells in the spleen and lymph nodes during infection, IL-33 signals through the ST2 receptor on activated CD8+ T cells, …
References (Sources)
- Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 + T-cell responses to acute and chronic viral infection
- IL-33 augments virus-specific memory T cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccine
- IL-33 in T cell differentiation, function, and immune homeostasis
- IL-33 synergizes with TCR and IL-12 signaling to promote the effector function of CD8 + T cells
- Interleukin-33 reinvigorates antiviral function of viral-specific CD8 + T Cells in Chronic Hepatitis B Virus Infection
- Overview of the IL-1 family in innate inflammation and acquired immunity
- Replicating viral vector platform exploits alarmin signals for potent CD8(+) T cellmediated tumour immunotherapy