meRfi®-GM
Amyloid-beta (Aß, Abeta) / Amyloid Plaques
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Contents
Accumulation of beta-amyloid is a common pathology in AD.
Beta-amyloid (Aß) is a peptide derived from the proteolytic cleavage of an APP.
Fibril-structured amyloid-beta (Aβ) oligomers have potent antimicrobial properties.
These can trap [pathogens](brain://aKAC0T2fKU6Ss8xccKia4A/PathogensPathobi…
References (Sources)
- Are antibodies directed against amyloid-β (Aβ) oligomers the last call for the Aβ hypothesis of Alzheimer's disease?
- Bacterial Extracellular DNA Promotes β-Amyloid Aggregation
- Brain-Gut-Microbiota Axis in Alzheimer’s DiseaseReview
- Changes of the enteric nervous system in amyloid-beta protein precursor transgenic mice correlate with disease progression
- Cysteine-rich domain of scavenger receptor AI modulates the efficacy of surface targeting and mediates oligomeric Aβ internalization
- Probiotics for Alzheimer’s Disease: A Systematic Review
- Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer’s Disease