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Many multicellular organisms have symbiotic microbes. Some relationships are commensal. This means one species benefits without affecting the other. Many relationships are mutualistic. They provide benefits to both organisms.
Microorganisms and their interactions play a vital role in various physiological and pathological processes, such as reproduction, immune system activity, cancer, and metabolic disorders
Humans have used microbes for centuries making beer, bread, and drugs. Traditionally, one species was used. But in nature, microbes work together forming communities.
see also:
Cancer microbiome / Tumor microbiota
Human microbiota / Human microbiome