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Sugar
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Contents
The vast majority of available sugars in the large intestine are diet and host-derived complex carbohydrates which are indigestible by the host.
A high-sugar diet unbalances the microbiome, so the body makes fewer of the gut immune cells that help to prevent metabolic disorders
The vagus nerve responds to sugars and sweeteners
The vagal response to sugars, sugar analogs and non-caloric [sweeteners](brain://pT4KXXfrvU2xf6M4x…
References (Sources)
- Dietary sugar and body weight: have we reached a crisis in the epidemic of obesity and diabetes?: health be damned! Pour on the sugar
- Fermentation of mucin and plant polysaccharides by strains of Bacteroides from the human colon
- Hypothalamic detection of macronutrients via multiple gut-brain pathways
- Mammalian sweet taste receptors
- Resolved: there is sufficient scientific evidence that decreasing sugar-sweetened beverage consumption will reduce the prevalence of obesity and obesity-related diseases
- The preference for sugar over sweetener depends on a gut sensor cell
- The receptors for mammalian sweet and umami taste