Experimental Colitis

Fusobacterium nucleatum - Extracellular Vesicles (EV) significantly aggravated experimental colitis in mice associated with Fn-EV–mediated downregulation of miR-574-5p expression and autophagy activation
Wei et al. 2023 Inflammatory Bowel Diseases 29: 9-26

Blockade of autophagy using chloroquine alleviates barrier damage exacerbated by Fusobacterium nucleatum - Extracellular Vesicles (EV) in vitro and in vivo
Wei et al. 2023 Inflammatory Bowel Diseases 29: 9-26

Inhibition of the miR-574-5p/ CARD3 axis reduced the severity of colitis, epithelial barrier damage, and autophagy activation induced by Fusobacterium nucleatum - Extracellular Vesicles (EV)
Wei et al. 2023 Inflammatory Bowel Diseases 29: 9-26

DSS, 2,4,6-trinitrobenzene sulfonic acid (TNBS)), and Oxazolone (OXA)) are three commonly used chemical drugs.
Hu et al. 2021c Front. Med. 8: 766126

Experimental colitis induced by chemical drugs has become the most common animal model of Ulcerative colitis (UC). The serum inflammatory cytokine levels and intestinal flora changes in a self-healing murine model of ulcerative colitis is induced by dextran sodium sulfate.
Jialing et al. 2020 Life Sci 263: 118587

Recombinant lactococci and lactobacilli strains expressing antiproteases and antioxidant enzymes have been tested successfully for their prophylactic and therapeutic effects in murine models of colitis
Bermúdez-Humarán et al. 2013

see also:
Colitis / Intestinal inflammation