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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Interleukin-1 (IL-1) beta (IL-1F2)

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Interleukin-1 (IL-1) beta (IL-1F2) is primarily produced by phagocytes in response to MAMPs that induce transcription of IL-1beta mRNA, whereas inflammasomes promote proteolytic activation of IL-1beta and assembly of gasdermin pores, facilitating non-canonical secretion of the active cytokine and induction of pyroptosis
Malik & Kanneganti 2017 J. Cell Sci. 130: 3955–3963

IL-1 is required for tum…

Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages
Brough et al. 2003 J. Immunol. 170: 3029-3036
Dendritic Cells Use Macropinocytosis and the Mannose Receptor to Concentrate Macromolecules in the Major Histocompatibility Complex Class II Compartment: Downregulation by Cytokines and Bacterial Products
Sallusto et al. 1995
IL-1 is required for tumor invasiveness and angiogenesis
Voronov et al., 2003
IL-1ß Enhances CD40 Ligand-Mediated Cytokine Secretion by Human DC: A Mechanism for T Cell-Independent DC Activation
Luft et al. 2002
IL-1ß Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells
Weiss et al. 2019a J. Immunol 203: 911
Innate and adaptive effects of inflammasomes on T cell response
Dostert et al. 2013
The MDM2-p53 pathway revisited
Nag et al. 2013 J Biomed Res. 27: 254-71

12/16/2025