meRfi®-GM
Chemokine (C-X-C motif) ligand 10 (CXCL10)
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Contents
Interferons (especially Interferon Type II (IFN Type II) / Interferon Gamma (IFN-g)) stimulate the production of Chemokine (C-X-C motif) ligand 10 (CXCL10) esp. in macrophages and dendritic cells, which recruits additional lymphocytes (especially Cytotoxic T cell (CTL), CD4+ Th1 Cells) and macrophages to the site of infection. Mechanistically, the cells express C-X-C chemokine receptor type 3 (CXCR3), the receptor for Chemokine (C-X-C motif) ligand 9 (CXCL9),…
References (Sources)
- HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages
- Janeway’s Immunobiology 10th
- Lactocepin secreted by Lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines
- Oncostatin M synergistically induces CXCL10 and ICAM-1 expression in IL-1beta-stimulated-human gingival fibroblasts
- Pathogenic Roles of CXCL10 in Experimental Autoimmune Prostatitis by Modulating Macrophage Chemotaxis and Cytokine Secretion
- Regulation of intestinal immunity and tissue repair by enteric glia