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Drugs, whether endogenous or exogenous, are affected by enterohepatic recirculation. In the liver, drugs and their metabolites undergo glucuronidation. This process involves Uridine diphosphate glucuronosyltransferase / . The result is drug-glucuronide conjugates. These conjugates are excreted through the intestinal tract. However, gut microbial [beta-glucuronidases](brain://5RMtT_Mrok6d9ukpQ…