meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Chemotherapy (CT) & Gut microbiota
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Contents
Modulation by Gut Microbiota
Studies have demonstrated that gut microbiota modifies the effect of chemotherapy (CT).
Gut microbiota modulates the activity, efficacy, and toxicity of several chemotherapy agents, such as:
- Gemcitabine
- Cyclophosphamide
- Irinotecan
- Cisplatin
- Fluorouracil (5-FU)
Additionally, it affects [targeted therapies](brain://U…
References (Sources)
- 16S rRNA gene pyrosequencing reveals shift in patient faecal microbiota during high-dose chemotherapy as conditioning regimen for bone marrow transplantation
- Gut microbiome associated with the psychoneurological symptom cluster in patients with head and neck cancers
- Gut microbiota and cancer: how gut microbiota modulates activity, efficacy and toxicity of antitumoral therapy
- Local bacteria affect the efficacy of chemotherapeutic drugs
- Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
- Systematic review of agents for the management of gastrointestinal mucositis in cancer patientsReview
- The efficacy and safety of probiotics in people with cancer: a systematic review