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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

CD284 (Toll-Like Receptor 4 (TLR-4)) & Inflammation / Inflammatory Diseases

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CD284 (Toll-Like Receptor 4 (TLR-4)) recognizes lipopolysaccharide (LPS) and drives the secretion of pro-inﬂammatory cytokines, often contributing to sepsis.
Schappe et al. 2018 Immunity 48: 59-74

Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation
Schappe et al. 2018 Immunity 48: 59-74
Targeting TLR4-dependent inflammation in post-hemorrhagic brain injury
Karimy et al. 2020 Expert Opinion on Therapeutic Targets 24: 525-533
Review

5/29/2026