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Oxysterols
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Contents
Oxysterols interact with the liver X receptor (LXR), which is considered to be particularly important concerning inflammatory processes and metabolic diseases (hyperlipidemia, atherosclerosis)
Oxysterols are becoming pivotal bioactive lipids which have been underestimated for a long time. Their actions are ranging from regulation of energy homeostasis (i.e., glucose and lipid metabolism) to inflammation and immunity, thereby opening the avenue to new treatments …
References (Sources)
- Current trends in oxysterol research
- Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
- Oxysterol sensing through the receptor GPR183 promotes the lymphoid-tissue-inducing function of innate lymphoid cells and colonic inflammation
- Oxysterols in intestinal immunity and inflammation
- Oxysterols: From Physiological Tuners to Pharmacological Opportunities
- The Liver under the Spotlight: Bile Acids and Oxysterols as Pivotal Actors Controlling MetabolismReview