meRfi®-GM
Genotoxins / Genotoxicity
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Among the most well-described genotoxic bacteria are enterotoxigenic Bacteroides fragilis (ETBF) () that produce Bacteroides fragilis toxin (BFT), strains of Escherichia coli or other bacteria that produce colibactin (), and Campylobacter jejuni strains that express Cytolethal distending toxin (CDT)…
References (Sources)
- A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein
- A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
- Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites
- Escherichia coli induces DNA double-strand breaks in eukaryotic cells
- Microbial metabolites damage DNA