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Chronic active gastritis A protein (CagA-Oncoprotein) can activate the p70 S6 kinase pathway and promotes CD274 (Programmed death-ligand 1 (PD-L1) expression
Chronic active gastritis A protein (CagA-Oncoprotein)-mediated beta-catenin activation leads to up-regulation of genes involved in cellular proliferation, survival, and migration, as well as angiogenesis - all processes central to carcinogenesis
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