meRfi®-GM
Tryptophan metabolism
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Navigation
Contents
Tryptophan follows three metabolic fates:
- Incorporation into proteins.
- Production of indoles.
- Breakdown into kynurenine.
Tryptophan is first deaminated to 3-indolepyruvate. It is then decarboxylated to indole acetaldehyde by indolepyruvate decarboxylase. This latter compound is transformed to tryptophol by alcohol dehydrogenase
Gut microbiota, which are the microorganisms living in our digestive …
References (Sources)
- Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis
- Fucose Ameliorates Tryptophan Metabolism and Behavioral Abnormalities in a Mouse Model of Chronic Colitis
- Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis
- Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism
- Microorganisms, Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status
- Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
- Tryptophan and indole metabolism in immune regulation