Anti-tumor immune responses

Anti-tumor immune responses refer to the actions taken by the body's immune system to recognize, attack, and destroy cancer cells. These responses involve both innate and adaptive immune mechanisms, such as activation of cytotoxic T lymphocytes, natural killer cells, macrophages, and production of antibodies against tumor-specific antigens. If effective, these processes can lead to tumor control or elimination, while failures in immune response or active immune suppression by the tumor often result in tumor progression (1, 2, 3, 4, 5)

Anti-tumor immune responses defined as high densities of memory T cells in the core and in the invasive margin of the tumors (6)

References:

(1) Munhoz & Postow 2016 F1000Res 5: 2545
(2) Naga Anusha et al. 2011 J Cancer Sci Ther S17
(3) Disis 2010 J Clin Oncol 28(29): 4531-8
(4) Motz & Coukos 2013 Immunity 39(1): 61-73
(5) Medler et al. 2015 Trends Cancer 1(1): 66-75
(6) Fridman et al. 2012

see also:
Anti-tumor T Cell Function
Cancer Immunotherapy / Immuno-Oncology
Tumor Immune Response
Tumor-Infiltrating Lymphocytes (TILs) & Tumors