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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Biological effects / Functions & Short-Chain Fatty Acids (SCFAs)

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Intestinal epithelial cells and immune cells take up Short-Chain Fatty Acids (SCFAs) through monocarboxylate transporters and/or sense SCFA signals via G protein-coupled receptors (GPCRs) on the cell surface.
Nagata et al. 2024 J Immunol 212(5): 771

Short-chain fatty acids (SCFAs) offer numerous health benefits: anti-inflammatory, immunoregulatory, [antiobesity](brain://ejIwuyJEJ0id1…

Butyrate attenuated fat gain through gut microbiota modulation in db/db mice following dapagliflozin treatment
Oh et al. 2019a Sci Rep 9: 20300
Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms?
Chambers et al. 2015a Proc Nutr Soc 74: 328-36
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
Koh et al. 2016 Cell 165: 1332
Review
Gut microbiota-derived short chain fatty acids are potential mediators in gut inﬂammation
Akhtar et al. 2022 Anim Nutr 8: 350-360
Review
Health beneﬁts and side effects of short-chain fatty acids
Xiong et al. 2022 Foods 11: 2863
Review
Microbiota-produced succinate improves glucose homeostasis via intestinal gluconeogenesis
De Vadder et al. 2016 Cell Metab 24: 151-157
NF-κB Regulation by Gut Microbiota Decides Homeostasis or Disease Outcome During Ageing
Zhang et al. 2022g Front. Cell Dev. Biol. 10: 874940
Review

12/16/2025