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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Enteroendocrine Cells (EEC)

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Enteroendocrine cells release hormones and neurotransmitters to regulate nutrient absorption, digestion, motility, feeding behaviours and sensory perception.
Gribble & Reimann 2016 Annu Rev Physiol 78: 277-299
Kaelberer et al. 2018 Science 361: eaat5236
Gribble et al. 2019 Nat. Rev. Endocrinol. 15: 226-237
Liddle 2019 Cell Mol. Gastroenterol. Hepatol. 7: 739-747

One percent of the intestinal epithelium is represented by the Enteroendocrine Cells (EEC)
Rezzani et al. 2022 Int. J. Mol. Sci. 23: 3758

enteroendocrine cells open and closed type

Based on their cytoarchitecture and location, Enteroendocrine Cells (EEC) are divided into open type, with a bottle-neck shape and a pr…

References (Sources)

A gut–brain neural circuit for nutrient sensory transduction
Kaelberer et al. 2018 Science 361: eaat5236
Classiﬁcation and functions of enteroendocrine cells of the lower gastrointestinal tract
Gunawardene et al. 2011 Int J Exp Pathol 92: 219-231
Review
Function and mechanisms of enteroendocrine cells and gut hormones in metabolism
Gribble et al. 2019 Nat. Rev. Endocrinol. 15: 226-237
Review
Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-inducible Stem Cell Activity
Yan et al. 2017 Cell Stem Cell 21: 78-90
Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas
Pearse et al. 1971 Gut 12: 783-788
The functional characterization of normal and neoplastic human enterochromafﬁn cells
Modlin et al. 2006 J Clin Endocrinol Metab 91: 2340-2348
Using Diverse Model Systems to Deﬁne Intestinal Epithelial Defenses to Enteric Viral Infections
Segrist & Cherry 2020 Cell Host & Microbe 27: 329-344
Review

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Enteroendocrine cell - Wikipedia